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Based on clinical patterns and research shared in my articles like "High Homocysteine, MTHFR Mutations, and the Inflammation Crisis," here are the major risks: Chronic Inflammation and Pain : Elevated homocysteine ramps up cytokines like IL-8 (neutrophil recruiter) and MCP-1 (monocyte attractor), leading to widespread aches, muscle tenderness, and "thermal runaway" inflammation

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doi: 10.1016/s0197-4580(02)00065-9 19 BrochardV.CombadireB.PrigentA.LaouarY.PerrinA.Beray-BerthatV.et al